Article

Novel Ultra-Rare Exonic Variants Identified in a Founder Population Implicate Cadherins in Schizophrenia

2020-05-30

Abstract excerpt

<h4>Summary</h4> Identification of rare genetic variants associated with schizophrenia has proven challenging due to multiple sources of heterogeneity, which may be reduced in founder populations. We examined ultra-rare exonic variants in 786 patients with schizophrenia and 463 healthy comparison subjects, all drawn from the Ashkenazi Jewish population. Cases had a higher frequency of novel missense or loss of fun...

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Literature Corpus work: ec0a3e79-eb58-56ed-b6fb-3d21cae1238f
DOI: 10.1101/2020.05.29.20115352

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