Article
Bipolar I disorder and schizophrenia: a 440-single-nucleotide polymorphism screen of 64 candidate genes among Ashkenazi Jewish case-parent trios.
American journal of human genetics - 1 Dec 2005
Fallin M Daniele, Lasseter Virginia K, Avramopoulos Dimitrios, Nicodemus Kristin K, Wolyniec Paula S, McGrath John A, Steel Gary, Nestadt Gerald, Liang Kung-Yee, Huganir Richard L, Valle David, Pulver Ann E
Abstract excerpt
Bipolar, schizophrenia, and schizoaffective disorders are common, highly heritable psychiatric disorders, for which familial coaggregation, as well as epidemiological and genetic evidence, suggests overlapping etiologies. No definitive susceptibility genes have yet been identified for any of these disorders. Genetic heterogeneity, combined with phenotypic imprecision and poor marker coverage, has contributed to...
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