Article

Rare schizophrenia risk variant burden is conserved in diverse human populations

2022-01-03

Abstract excerpt

Schizophrenia is a chronic mental illness that is amongst the most debilitating conditions encountered in medical practice. A recent landmark schizophrenia study of the protein-coding regions of the genome identified a causal role for ten genes and a concentration of rare variant signals in evolutionarily constrained genes 1 . This study -- and most other large-scale human genetic studies -- was mainly composed of...

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Literature Corpus work: c415d89d-ca5d-5ac2-9397-b313bd1f2f06
DOI: 10.1101/2022.01.03.22268662

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