A cytogenetic abnormality and rare coding variants identify ABCA13 as a candidate gene in schizophrenia, bipolar disorder, and depression.

doi:10.1016/j.ajhg.2009.11.003

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Article

A cytogenetic abnormality and rare coding variants identify ABCA13 as a candidate gene in schizophrenia, bipolar disorder, and depression.

American journal of human genetics - 1 Dec 2009

Knight Helen M, Pickard Benjamin S, Maclean Alan, Malloy Mary P, Soares Dinesh C, McRae Allan F, Condie Alison, White Angela, Hawkins William, McGhee Kevin, van Beck Margaret, MacIntyre Donald J, Starr John M, Deary Ian J, Visscher Peter M, Porteous David J, Cannon Ronald E, St Clair David, Muir Walter J, Blackwood Douglas H R

Abstract excerpt

Schizophrenia and bipolar disorder are leading causes of morbidity across all populations, with heritability estimates of approximately 80% indicating a substantial genetic component. Population genetics and genome-wide association studies suggest an overlap of genetic risk factors between these illnesses but it is unclear how this genetic component is divided between common gene polymorphisms, rare genomic copy...

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Identifiers

PMID: 19944402
DOI: 10.1016/j.ajhg.2009.11.003
PMCID: PMC2790560

Genes

ABCA13

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