Article

Detection of A-to-I microRNA editing with miRmedon reveals widespread co-editing of mature microRNA in the human brain

2022-12-23

Abstract excerpt

<h4>ABSTRACT</h4> microRNA (miRNA), key regulators of gene expression, are prime targets for adenosine deaminase acting on RNA (ADAR) enzymes. Although ADAR-mediated adenosine-to-inosine (A-to-I) miRNA editing has been shown to be essential for orchestrating complex processes, including neurodevelopment and cancer progression, only few human miRNA editing sites have been reported. Several computational approaches...

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Literature Corpus work: eb9aa132-c1be-5126-ae99-ac7e72aa3659
DOI: 10.1101/2022.12.23.521716

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