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Article

Comprehensive analysis of RNA-Seq data reveals extensive RNA editing in a human transcriptome.

Nature biotechnology - 12 Feb 2012

Peng Zhiyu, Cheng Yanbing, Tan Bertrand Chin-Ming, Kang Lin, Tian Zhijian, Zhu Yuankun, Zhang Wenwei, Liang Yu, Hu Xueda, Tan Xuemei, Guo Jing, Dong Zirui, Liang Yan, Bao Li, Wang Jun

Abstract excerpt

RNA editing is a post-transcriptional event that recodes hereditary information. Here we describe a comprehensive profile of the RNA editome of a male Han Chinese individual based on analysis of ∼767 million sequencing reads from poly(A)(+), poly(A)(-) and small RNA samples. We developed a computational pipeline that carefully controls for false positives while calling RNA editing events from genome and...

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PMID: 22327324
DOI: 10.1038/nbt.2122

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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