Article

Cellular and genetic drivers of RNA editing variation in the human brain

2021-07-16

Abstract excerpt

<h4>ABSTRACT</h4> Posttranscriptional adenosine-to-inosine modifications amplify the functionality of RNA molecules in the brain, yet the cellular and genetic regulation of RNA editing is poorly described. We quantified base-specific RNA editing across three major cell populations from the human prefrontal cortex: glutamatergic neurons, medial ganglionic eminence GABAergic neurons, and oligodendrocytes. We found...

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Literature Corpus work: 737cf80b-5ef2-53b3-bf9c-14a993304293
DOI: 10.1101/2021.07.16.452690

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