Article

Co-expression in tissue-specific gene networks links genes in cancer-susceptibility loci to known somatic driver genes

2023-09-08

Abstract excerpt

<h4>Background</h4> The genetic background of cancer remains complex and challenging to integrate. Many somatic mutations in genes are known to cause and drive cancer, while genome-wide association studies (GWAS) of cancer have revealed many germline risk factors associated with cancer. However, the overlap between known somatic driver genes and positional candidate genes from GWAS loci is surprisingly small. We h...

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Literature Corpus work: ea67337e-dff9-53d0-b2e3-5fee15e5cfe0
DOI: 10.1101/2023.09.08.23295254

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