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Article

Investigating the tissue specificity and prognostic impact of cis-regulatory cancer risk variants.

Human genetics - 1 Sept 2023

Subramanian Ajay, Su Shengqin, Moding Everett J, Binkley Michael Sargent

Abstract excerpt

The tissue-specific incidence of cancers and their genetic basis are poorly understood. Although prior studies have shown global correlation across tissues for cancer risk single-nucleotide polymorphisms (SNPs) identified through genome-wide association studies (GWAS), any shared functional regulation of gene expression on a per SNP basis has not been well characterized. We set to quantify cis-mediated gene...

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PMID: 37474751
DOI: 10.1007/s00439-023-02586-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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