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Article

Cryo-EM structure of the bicarbonate receptor GPR30

2024-05-19

Abstract excerpt

G-protein-coupled receptor 30 (GPR30) is a bicarbonate receptor that plays a vital role in cellular responses to extracellular pH and ion homeostasis. Despite its significance, the mechanisms by which GPR30 interacts with bicarbonate ions remain elusive. There is no consensus on a drug that targets GPR30, and difficulties in pharmacological analyses have limited biological and drug discovery research on GPR30. Her...

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Identifiers and source

Literature Corpus work
ea470b66-580e-5239-8a3e-b6200611c30c
DOI
10.1101/2024.05.19.594840
Open publication

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Cryo-EM structure of the bicarbonate receptor GPR30DOI 10.1101/2024.05.19.594840
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