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Article

Recent advances in calcium-sensing receptor structures and signaling pathways.

Progress in molecular biology and translational science - 1 Jan 2023

Gorvin Caroline M

Abstract excerpt

The calcium-sensing receptor (CaSR) is a class C GPCR that has a fundamental role in extracellular calcium homeostasis by regulating parathyroid hormone release and urinary calcium excretion. Germline mutations in the receptor cause disorders of calcium homeostasis and studies of the functional effects of these mutations has facilitated understanding of CaSR signaling and how allosteric modulators affect these...

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PMID: 36707151
DOI: 10.1016/bs.pmbts.2022.06.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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