Article

To be or not to be an ion channel: cryo-EM structures have a say

2023-04-24

Abstract excerpt

Identification of previously unknown ion channels is always a challenging work though the transmembrane protein-coding genes in human genome has been comprehensively annotated for years. Despite being the gold standard of functional assay for ion channels, electrophysiological recordings are often accompanied by electrical noise, leak conductance and background currents of the membrane system. These unwanted signa...

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Literature Corpus work: d4c6a991-1419-5fd5-aa16-87144f549fea
DOI: 10.22541/au.168234501.14749496/v1

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