Article

A GWAS-Derived Polygenic Score for Interleukin-1β is Associated with Hippocampal Volume in Two Samples

2019-01-14

Abstract excerpt

Accumulating research suggests that the pro-inflammatory cytokine interleukin-1β (IL-1β) has a modulatory effect on the hippocampus, a brain structure important for learning and memory as well as linked with both psychiatric and neurodegenerative disorders. Here, we use an imaging genetics strategy to test an association between an IL-1β polygenic score, derived from summary statistics of a recent genome-wide asso...

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Literature Corpus work: e9a96f83-a733-5ab6-8227-b472c54da775
DOI: 10.1101/516989

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