Article
A Genome-Wide Association Study Suggests Novel Loci Associated with a Schizophrenia-Related Brain-Based Phenotype.
PloS one - 1 Jan 2013
Hass Johanna, Walton Esther, Kirsten Holger, Liu Jingyu, Priebe Lutz, Wolf Christiane, Karbalai Nazanin, Gollub Randy, White Tonya, Roessner Veit, Müller Kathrin U, Paus Tomas, Smolka Michael N, Schumann Gunter, Scholz Markus, Cichon Sven, Calhoun Vince, Ehrlich Stefan
Abstract excerpt
Patients with schizophrenia and their siblings typically show subtle changes of brain structures, such as a reduction of hippocampal volume. Hippocampal volume is heritable, may explain a variety of cognitive symptoms of schizophrenia and is thus considered an intermediate phenotype for this mental illness. The aim of our analyses was to identify single-nucleotide polymorphisms (SNP) related to hippocampal volume...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.