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Article

Circulating biomarkers of immunity and inflammation, risk of Alzheimer's disease, and hippocampal volume: a Mendelian randomization study.

Translational psychiatry - 17 May 2021

Fani Lana, Georgakis Marios K, Ikram M Arfan, Ikram M Kamran, Malik Rainer, Dichgans Martin

Abstract excerpt

The aim of this study was to explore the association between genetically predicted circulating levels of immunity and inflammation, and the risk of Alzheimer's disease (AD) and hippocampal volume, by conducting a two-sample Mendelian Randomization Study. We identified 12 markers of immune cells and derived ratios (platelet count, eosinophil count, neutrophil count, basophil count, monocyte count, lymphocyte...

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Identifiers

PMID: 34001857
DOI: 10.1038/s41398-021-01400-z
PMCID: PMC8129147

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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