Article
Functional impact of a recently identified quantitative trait locus for hippocampal volume with genome-wide support.
Translational psychiatry - 23 Jul 2013
Erk S, Meyer-Lindenberg A, Schmierer P, Grimm O, Tost H, Mühleisen T, Mattheisen M, Seiferth N, Cichon S, Rietschel M, Nöthen M M, Heinz A, Walter H
Abstract excerpt
In a large brain-imaging study, a multinational consortium has recently identified a common genetic variation in rs7294919 being associated with hippocampal volume. Here, we explored whether this quantitative trait locus also affects hippocampal function using a previously established reliable neuroimaging paradigm. We observed a significant effect of rs7294919 variation in the right hippocampus showing that...
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