Article
Distributed genetic architecture across the hippocampal formation implies common neuropathology across brain disorders.
Nature communications - 15 Jun 2022
Bahrami Shahram, Nordengen Kaja, Shadrin Alexey A, Frei Oleksandr, van der Meer Dennis, Dale Anders M, Westlye Lars T, Andreassen Ole A, Kaufmann Tobias
Abstract excerpt
Despite its major role in complex human functions across the lifespan, most notably navigation, learning and memory, much of the genetic architecture of the hippocampal formation is currently unexplored. Here, through multivariate genome-wide association analysis in volumetric data from 35,411 white British individuals, we reveal 177 unique genetic loci with distributed associations across the hippocampal...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.