Article
Heritability of Regional Brain Volumes in Large-Scale Neuroimaging and Genetic Studies.
Cerebral cortex (New York, N.Y. : 1991) - 5 Jul 2019
Zhao Bingxin, Ibrahim Joseph G, Li Yun, Li Tengfei, Wang Yue, Shan Yue, Zhu Ziliang, Zhou Fan, Zhang Jingwen, Huang Chao, Liao Huiling, Yang Liuqing, Thompson Paul M, Zhu Hongtu
Abstract excerpt
Brain genetics is an active research area. The degree to which genetic variants impact variations in brain structure and function remains largely unknown. We examined the heritability of regional brain volumes (P ~ 100) captured by single-nucleotide polymorphisms (SNPs) in UK Biobank (n ~ 9000). We found that regional brain volumes are highly heritable in this study population and common genetic variants can...
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