Article

GWAS of 19,629 individuals identifies novel genetic variants for regional brain volumes and refines their genetic co-architecture with cognitive and mental health traits

2019-03-25

Abstract excerpt

Volumetric variations of human brain are heritable and are associated with many brain-related complex traits. Here we performed genome-wide association studies (GWAS) and post-GWAS analyses of 101 brain volumetric phenotypes using the UK Biobank (UKB) sample including 19,629 participants. GWAS identified 287 independent SNPs exceeding genome-wide significance threshold of 4.9*10 −10 , adjusted for testing multipl...

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Literature Corpus work: da4ed03b-8e3e-5dc8-8fea-33a4d35363c9
DOI: 10.1101/586339

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