Article

Myosin-binding protein C forms C-links and stabilizes OFF states of myosin

2023-09-12

Abstract excerpt

Contraction force in muscle is produced by the interaction of myosin motors in the thick filaments and actin in the thin filaments and is fine-tuned by other proteins such as myosin-binding protein C (MyBP-C). One form of control is through the regulation of myosin heads between an ON and OFF state in passive sarcomeres, which leads to their ability or inability to interact with the thin filaments during contracti...

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Literature Corpus work: e96a0985-617c-54b0-877f-0a4e25bdda1c
DOI: 10.1101/2023.09.10.556972

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