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SKELETAL MyBP-C ISOFORMS TUNE THE MOLECULAR CONTRACTILITY OF DIVERGENT SKELETAL MUSCLE SYSTEMS

2019-06-21

Abstract excerpt

<h4>ABSTRACT</h4> Skeletal muscle myosin-binding protein C (MyBP-C) is a myosin thick filament-associated protein; localized through its C terminus to distinct regions (C-zones) of the sarcomere. MyBP-C modulates muscle contractility, presumably through its N terminus extending from the thick filament and interacting with either the myosin head region and/or the actin thin filament. Two isoforms of MyBP-C (fast-...

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Literature Corpus work
c611f5b2-05d7-500b-99f1-9d0394edb06b
DOI
10.1101/676601
Open publication

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