Article
Signaling and myosin-binding protein C.
The Journal of biological chemistry - 25 Mar 2011
James Jeanne, Robbins Jeffrey
Abstract excerpt
Myosin-binding protein C (MyBP-C) is a thick filament protein consisting of 1274 amino acid residues (149 kDa) that was identified by Starr and Offer over 30 years ago as a contaminant present in a preparation of purified myosin. Since then, numerous studies have defined the muscle-specific isoforms, the structure, and the importance of the proteins in normal striated muscle structure and function. Underlying the...
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