Article

Single-cell transcriptomics reveals a conserved embryonic progenitor in different human cancers

2025-12-13

Abstract excerpt

Cellular plasticity, a critical feature of embryonic development, is often reactivated in cancer, enabling tumor cells to acquire stem-like properties and facilitate uncontrolled growth. This study compares cellular plasticity in cancer and early human development by integrating single-cell data from three cancers and embryoid bodies. The analysis identifies a shared, highly proliferative progenitor-like state, dr...

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Literature Corpus work: e91b6375-3442-5fde-b443-fd091a9d3ee2
DOI: 10.64898/2025.12.11.693590

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