Article

Deciphering cell lineage specification of human lung adenocarcinoma with single-cell RNA sequencing

2021-01-07

Abstract excerpt

Lung adenocarcinomas (LUAD) start as precancerous lesions such as atypical adenomatous hyperplasia (AAH), develop stepwise into adenocarcinoma in situ (AIS) and minimally invasive adenocarcinoma (MIA), then eventually progress toward invasive adenocarcinoma (IA). To date the cellular heterogeneity across these distinct clinical stages and the underlying molecular events driving tumor progression remain largely unc...

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Literature Corpus work: f7fe703e-ea20-5d33-bedb-c51e6c250321
DOI: 10.21203/rs.3.rs-127270/v1

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