Article

1-Methylnicotinamide is an immune regulatory metabolite in human ovarian cancer

2020-05-07

Abstract excerpt

<h4>ABSTRACT</h4> Immune regulatory metabolites are key features of the tumor microenvironment (TME), yet with a few notable exceptions, their identities remain largely unknown. We uncovered the immune regulatory metabolic states and metabolomes of sorted tumor and stromal, CD4+, and CD8+ cells from the tumor and ascites of patients with high-grade serous ovarian cancer (HGSC) using high-dimensional flow cytometr...

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Literature Corpus work: e64a1c4e-e5ed-5fae-bc29-a6f7dbd579dc
DOI: 10.1101/2020.05.05.077990

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