Article
Immune cell metabolism in cancer drug resistance: Advances in target discovery and clinical translation
1 Jan 2025
Abstract excerpt
Drug resistance continues to be the principal limiting factor in achieving a cure for patients with cancer, significantly hindering the long-term efficacy of novel cancer drugs. Accumulating evidence has shown that metabolites derived from tumor cells regulate immune cell metabolism via tumor microenvironment crosstalk. However, as immunometabolic research has deepened, the leading role played by the intrinsic...
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