Article

Gene expression is a poor predictor of the metabolite abundance in cancer cells

2021-12-20

Abstract excerpt

Metabolic reprogramming is a hallmark of cancer characterized by global changes in metabolite levels. However, compared with the study of gene expression, profiling of metabolites in cancer samples remains relatively understudied. We obtained metabolomic profiling and gene expression data from 454 human solid cancer cell lines across 24 cancer types from the Cancer Cell Line Encyclopedia (CCLE) database, to evalua...

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Literature Corpus work: 92c0d8bf-87ae-5132-aaf0-c9da16e118e6
DOI: 10.1101/2021.12.19.473333

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