Article

Inhibition of Glutamine Metabolism Suppresses Tumor Progression through Remodeling of the Macrophage Immune Microenvironment

2025-01-14

Abstract excerpt

<h4>Background</h4> Targeting glutamine metabolism has emerged as a promising strategy in cancer therapy. However, several barriers, such as in vivo anti-tumor efficacy, drug toxicity, and safety, remain to be overcome to achieve clinical utility. Prior preclinical in vivo studies had generated encouraging data showing promises of cancer metabolism targeting drugs, although most were performed on immune-deficie...

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Literature Corpus work: 9b2d4e6f-dbf0-5738-8a06-c2fadc12f635
DOI: 10.1101/2025.01.10.632174

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