Article

A Pan-Cancer Atlas of Metabolic Regulatory Circuitries Integrating Multi-Omic, Immune, and Clinical Dimensions

2025-12-10

Abstract excerpt

<title>Abstract</title> <p> <bold>Background</bold> Metabolic reprogramming is a defining component of tumor progression, immune evasion, and susceptibility to regulated cell death, yet the organization of these processes across multi-omic, immune, and clinical dimensions remains unresolved. <bold>Results</bold> Here, we present a Pan-Cancer atlas of metabolic regulatory circuitries, reconstructed using OncoM...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 019cb1e4-645e-59f4-92c5-6ddd3b3a403d
DOI: 10.21203/rs.3.rs-8280481/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

A Pan-Cancer Atlas of Metabolic Regulatory Circuitries Integrating Multi-Omic, Immune, and Clinical DimensionsDOI 10.21203/rs.3.rs-8280481/v1Read

Pan-cancer analysis of transcriptional metabolic dysregulation using The Cancer Genome AtlasSemantic proximity Read

Pan-cancer metabolic landscapes: A multi-omics viewSemantic proximity Read

A Single-Cell Network Approach to Decode Metabolic Regulation in Gynecologic and Breast CancersSemantic proximity Read

Robust Metabolic Transcriptional Components in 34,494 Patient-Derived Samples and Cell LinesSemantic proximity Read

Glucose Metabolic Reprogramming in Cancer MicroenvironmentSemantic proximity Read

Gene Expression Integration into Pathway Modules Reveals a Pan-Cancer Metabolic Landscape.Semantic proximity Read

Pan-cancer characterization of metabolism-related biomarkers identifies potential therapeutic targetsSemantic proximity Read

Metabolic predictors of response to immune checkpoint blockade therapySemantic proximity Read

Metabolic pathway-based subtyping reveals distinct microenvironmental states associated with diffuse large B-cell lymphoma outcomes.Semantic proximity Read

Robust metabolic transcriptional components in 34,494 patient-derived samples and cell linesSemantic proximity Read

A Multimodal Atlas of Tumor Metabolism Reveals the Architecture of Gene-Metabolite Co-regulationSemantic proximity Read

Metabolic predictors of response to immune checkpoint blockade therapySemantic proximity Read