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Article

Multiplexed Single-cell Metabolic Profiles Organize the Spectrum of Cytotoxic Human T Cells

2020-01-17

Abstract excerpt

<h4>Summary</h4> Cellular metabolism regulates immune cell activation, differentiation and effector functions to the extent that its perturbation can augment immune responses. However, the analytical technologies available to study cellular metabolism lack single-cell resolution, obscuring metabolic heterogeneity and its connection to immune phenotype and function. To that end, we utilized high-dimensional, antib...

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Literature Corpus work
e25aac0e-7669-57ee-a901-c47671f844bf
DOI
10.1101/2020.01.17.909796
Open publication

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Multiplexed Single-cell Metabolic Profiles Organize the Spectrum of Cytotoxic Human T CellsDOI 10.1101/2020.01.17.909796
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