Article

Multiple links between 5-methylcytosine content of mRNA and translation

2020-02-04

Abstract excerpt

5-methylcytosine (m 5 C) is a prevalent base modification in tRNA and rRNA but it also occurs more broadly in the transcriptome, including in mRNA, where it serves incompletely understood molecular functions. In pursuit of potential links of m 5 C with mRNA translation, we performed polysome profiling of human HeLa cell lysates and subjected RNA from resultant fractions to efficient bisulfite conversion followed...

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Literature Corpus work: e55d4639-c38f-5127-922f-acddf16559a6
DOI: 10.1101/2020.02.04.933499

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