Article

Investigation of TRMT61B methyltransferase activity on mRNA and its effects on translation

2025-12-08

Abstract excerpt

<h4>ABSTRACT</h4> Despite recent advances in technology to map RNA chemical modifications transcriptome-wide, the distribution of N¹-methyladenosine (m¹A) in mRNA remains contested, hindering a clear understanding of its function. Additionally, the enzyme(s) that installs the majority of reported mRNA m 1 A sites has yet to be identified. In this study, we characterized TRMT61B, an m 1 A methyltransferase known...

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Literature Corpus work: 6f2101f8-6562-5d4e-87ca-342858a781ce
DOI: 10.64898/2025.12.08.692954

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