Article

Sequence- and structure-specific cytosine-5 mRNA methylation by NSUN6

2020-10-01

Abstract excerpt

<h4>ABSTRACT</h4> Methylation is the most common internal modification in mRNA. While the highly abundant N6-methyladonsine (m 6 A) modification affects most aspects of mRNA function, the precise functions of the rarer 5-methylcytosine (m 5 C) remains largely unknown. Here, we map m 5 C in the human transcriptome using methylation-dependent individual-nucleotide resolution cross-linking and immunoprecipitation...

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Literature Corpus work: bef354d3-d239-545e-a04b-f0e80c8fd043
DOI: 10.1101/2020.10.01.320036

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