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Article

m1A within cytoplasmic mRNAs at single nucleotide resolution: a reconciled transcriptome-wide map.

RNA (New York, N.Y.) - 1 Nov 2018

Schwartz Schraga

Abstract excerpt

Following synthesis, RNA can be modified with over 100 chemically distinct modifications. Recently, two studies-one by our group-developed conceptually similar approaches to globally map N1-methyladenosine (m1A) at single nucleotide resolution. Surprisingly, the studies diverged quite substantially in their estimates of the abundance, whereabouts, and stoichiometry of m1A within internal sites in cytosolic mRNAs:...

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Identifiers

PMID: 30131402
DOI: 10.1261/rna.067348.118
PMCID: PMC6191711

Genes

TRMT6

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