Article

Base-resolution mapping reveals distinct m <sup>1</sup> A methylome in nuclear- and mitochondrial-encoded transcripts

2017-10-13

Abstract excerpt

<h4>SUMMARY</h4> Gene expression can be post-transcriptionally regulated via dynamic and reversible RNA modifications. N 1 -methyladenosine (m 1 A) is a recently identified mRNA modification; however, little is known about its precise location, regulation and function. Here, we develop a base-resolution m 1 A profiling method, based on m 1 A-induced misincorporation during reverse transcription, and report di...

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Literature Corpus work: b994a561-7cba-584b-87d7-a7ae5e4e07fe
DOI: 10.1101/202747

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