Back to search

Article

Systematic identification of tissue-conserved m <sup>6</sup> A sites reveals a stable epitranscriptomic regulatory layer controlling essential genes

2026-03-20

Abstract excerpt

<h4>Summary</h4> Chemical modifications to RNA are fundamental regulators of cellular identity and function. Among these, N6-methyladenosine (m 6 A) is the most abundant mRNA modification in mammalian cell, governing major post-transcriptional processes. While conditional m 6 A dynamics are well studied, the extent and function of condition-independent, tissue-conserved (TC) m 6 A in humans remain unclear. Her...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
313fd5ac-3557-541a-acc2-f830b4695539
DOI
10.64898/2026.03.19.713046
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Systematic identification of tissue-conserved m <sup>6</sup> A sites reveals a stable epitranscriptomic regulatory layer controlling essential genesDOI 10.64898/2026.03.19.713046
Comprehensive analysis across mammalian tissues and cells decipher the underlying mechanism of m6A specificitySemantic proximity
Landscape and regulation of m <sup>6</sup> A and m <sup>6</sup> Am methylome across human and mouse tissuesSemantic proximity
Epigenetic Regulation of m6A Modifications in Human CancerSemantic proximity
Pan-cancer Analysis Reveals m <sup>6</sup> A Variation and Cell-specific Regulatory Network in Different Cancer TypesSemantic proximity
N <sup>6</sup> -Methyladenine DNA Modification in Human GenomeSemantic proximity
The three YTHDF paralogs and VIRMA are the major tumor drivers among the m <sup>6</sup> A core genes in a pan-cancer analysisSemantic proximity
m6A Modification in Coding and Non-coding RNAs: Roles and Therapeutic Implications in Cancer.Semantic proximity
Base-resolution mapping reveals distinct m <sup>1</sup> A methylome in nuclear- and mitochondrial-encoded transcriptsSemantic proximity
Landscape and Regulation of m6A and m6Am Methylome across Human and Mouse Tissues.Semantic proximity
Comprehensive profiling of <i>N</i> <sup>6</sup> -methyladnosine (m <sup>6</sup> A) readouts reveals novel m <sup>6</sup> A readers that regulate human embryonic stem cell differentiationSemantic proximity
N6-Methyladenosine Role in Cancer: Learning from AMLSemantic proximity
Main N6-Methyladenosine Readers: YTH Family Proteins in CancersSemantic proximity
Select a neighboring publication to make it the new centre.