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tRNA modifications: greasing the wheels of translation and beyond

26 Dec 2024

Abstract excerpt

Transfer RNA (tRNA) is one of the most abundant RNA types in cells, acting as an adaptor to bridge the genetic information in mRNAs with the amino acid sequence in proteins. Both tRNAs and small fragments processed from them play many nonconventional roles in addition to translation. tRNA molecules undergo various types of chemical modifications to ensure the accuracy and efficiency of translation and regulate...

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PMID: 39723662
DOI: 10.1080/15476286.2024.2442856

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