Article

An integrated polygenic and clinical risk tool enhances coronary artery disease prediction

2020-06-03

Abstract excerpt

<h4>Background</h4> There is considerable interest in whether genetic data can be used to improve standard cardiovascular disease risk calculators, as the latter are routinely used in clinical practice to manage preventative treatment. <h4>Methods</h4> This research has been conducted using the UK Biobank (UKB) resource. We developed our own polygenic risk score (PRS) for coronary artery disease (CAD), using novel...

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Literature Corpus work: e4fba7c8-e057-53c9-883a-00158615f379
DOI: 10.1101/2020.06.01.20119297

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