Article

Genomic risk prediction of coronary artery disease in nearly 500,000 adults: implications for early screening and primary prevention

2018-01-19

Abstract excerpt

<h4>Background</h4> Coronary artery disease (CAD) has substantial heritability and a polygenic architecture; however, genomic risk scores have not yet leveraged the totality of genetic information available nor been externally tested at population-scale to show potential utility in primary prevention. <h4>Methods</h4> Using a meta-analytic approach to combine large-scale genome-wide and targeted genetic associat...

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Literature Corpus work: 3d74174d-4c14-51b2-bb7d-b6bc1f9154e6
DOI: 10.1101/250712

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