Article

Integration of biomarker polygenic risk score improves prediction of coronary heart disease in UK Biobank and FinnGen

2022-08-23

Abstract excerpt

<h4>Background</h4> In addition to age and sex, also smoking history and levels of blood pressure, cholesterol, lipoproteins and inflammation are established biomarkers for coronary heart disease (CHD). As standard polygenic risk scores (PRS) have recently proven successful for CHD prediction, it remains of high interest to determine how a combined PRS of biomarkers (BioPRS) constructed from statistically relevant...

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Literature Corpus work: 9abe7855-c24f-52f5-8a91-392eb7fe510a
DOI: 10.1101/2022.08.22.22279057

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