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Article

Polygenic risk scores in coronary artery disease.

Current opinion in cardiology - 1 Jan 2023

Christiansen Morten Krogh, Nyegaard Mette, Jensen Henrik Kjærulf

Abstract excerpt

PURPOSE OF REVIEW: Recent advances in genetics have facilitated the calculation of polygenic risk scores (PRSs) based on common genetic risk variants of coronary artery disease (CAD). Here, we provide an explanation of the genetic basis for PRSs and review recent literature investigating PRSs and the clinical utility for different aspects of CAD. RECENT FINDINGS: CAD-based PRSs are strongly associated with...

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PMID: 36598448
DOI: 10.1097/HCO.0000000000001007

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