Article

Evaluation of CRISPR gene-editing tools in zebrafish

2020-10-19

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Zebrafish have practical features that make them a useful model for higher-throughput tests of gene function using CRISPR/Cas9 editing to create ‘knockout’ models. In particular, the use of G 0 mosaic mutants has potential to increase throughput of functional studies significantly but may suffer from transient effects of introducing Cas9 via microinjection. Further, a large...

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Literature Corpus work: e4fab6d3-35ac-583a-8c23-759130fea7d4
DOI: 10.1101/2020.10.19.345256

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