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New Developments in CRISPR/Cas-based Functional Genomics and their Implications for Research Using Zebrafish.

Current gene therapy - 1 Jan 2017

Prykhozhij Sergey V, Caceres Lucia, Berman Jason N

Abstract excerpt

INTRODUCTION: Genome editing using CRISPR/Cas9 has advanced very rapidly in its scope, versatility and ease of use. Zebrafish (Danio rerio) has been one of the vertebrate model species where CRISPR/Cas9 has been applied very extensively for many different purposes and with great success. In particular, disease modeling in zebrafish is useful for testing specific gene variants for pathogenicity in a preclinical...

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PMID: 29173171
DOI: 10.2174/1566523217666171121164132

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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