Article
Targeted candidate gene screens using CRISPR/Cas9 technology.
Methods in cell biology - 1 Jan 2016
Shah A N, Moens C B, Miller A C
Abstract excerpt
In the postgenomic era, the ability to quickly, efficiently, and inexpensively assign function to the zebrafish proteome is critical. Clustered regularly interspaced short palindromic repeats (CRISPRs) have revolutionized the ability to perform reverse genetics because of its simplicity and broad applicability. The CRISPR system is composed of an engineered, gene-specific single guide RNA (sgRNA) and a Cas9...
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