Article

Shared and Unique Evolutionary Trajectories to Ciprofloxacin Resistance in Gram-negative Bacterial Pathogens

2021-04-06

Abstract excerpt

The resistance to broad-spectrum antibiotic ciprofloxacin is detected in high rates for a wide range of bacterial pathogens. To investigate dynamics of ciprofloxacin resistance development we proposed a comparative resistomics workflow for three clinically relevant species of Gram-negative bacteria: Escherichia coli , Acinetobacter baumannii , and Pseudomonas aeruginosa . We combined experimental evolution in a...

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Literature Corpus work: e4a156f1-258f-595b-9760-3062656d141b
DOI: 10.1101/2021.04.06.438548

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