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<i>In vitro</i> evolution of ciprofloxacin resistance in <i>Neisseria</i> commensals and derived mutation population dynamics in natural <i>Neisseria</i> populations

2024-07-16

Abstract excerpt

Commensal Neisseria are members of a healthy human oropharyngeal microbiome; however, they also serve as a reservoir of antimicrobial resistance for their pathogenic relatives. Despite their known importance as sources of novel genetic variation for pathogens, we still do not understand the full suite of resistance mutations commensal species can harbor. Here, we use in vitro selection to assess the mutations th...

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Literature Corpus work
a767ed43-2e62-5509-9ddb-f5b3201104a7
DOI
10.1101/2024.07.16.603762
Open publication

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