Article

Genetic inhibition of <i>PCSK9</i> , atherogenic lipoprotein concentrations, and calcific aortic valve stenosis

2019-03-01

Abstract excerpt

<h4>Background</h4> Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibition reduces plasma concentrations of low-density lipoprotein cholesterol (LDL-C), apolipoprotein B (apoB) and lipoprotein(a) [Lp(a)]. Atherogenic lipoprotein levels have been linked with calcific aortic valve stenosis (CAVS). Our objectives were to determine the association between variants in PCSK9 and lipoprotein-lipid levels, cor...

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Literature Corpus work: e45711a8-8a76-531e-bfde-1c0b1f8f0c2d
DOI: 10.1101/560458

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