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Article

Genetics of Calcific Aortic Stenosis: A Systematic Review.

Genes - 10 Oct 2024

Vassiliou Vassilios S, Johnson Nicholas, Langlands Kenneth, Tsampasian Vasiliki

Abstract excerpt

Background: Calcific aortic stenosis is the most prevalent valvular abnormality in the Western world. Factors commonly associated with calcific aortic stenosis include advanced age, male sex, hypertension, diabetes and impaired renal function. This review synthesises the existing literature on genetic associations with calcific aortic stenosis. Methods: A systematic search was conducted in the PubMed, Ovid and...

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Aortic Valve
Aortic Valve Stenosis
Calcinosis
Delta-5 Fatty Acid Desaturase
Genetic Predisposition to Disease

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PMID: 39457433
DOI: 10.3390/genes15101309
PMCID: PMC11508093

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