Article

BRAF <sup>V600E</sup> induces reversible mitotic arrest in human melanocytes via microRNA-mediated suppression of AURKB

2020-05-24

Abstract excerpt

Benign melanocytic nevi frequently emerge when an acquired BRAF V600E mutation triggers unchecked proliferation and subsequent arrest in melanocytes. Recent observations have challenged the role of oncogene-induced senescence in melanocytic nevus formation, necessitating investigations into alternative mechanisms for the establishment and maintenance of proliferation arrest in nevi. We compared the transcriptomes...

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Literature Corpus work: e3c59f37-e8fc-58ed-8758-208bba652934
DOI: 10.1101/2020.05.21.109397

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