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Article

Establishment of Stable Immortalized Human Choroidal Melanocytes for Ocular Research

2026-02-17

Abstract excerpt

<h4>Purpose</h4> The short lifespan of primary normal choroidal melanocytes (NCMs) in vitro represents a major barrier to mechanistic, functional, and translational studies of choroid biology and uveal melanoma (UM). This study aimed to establish and characterize immortalized human NCM lines that retain melanocytic function, maintain a non-cancerous profile, and are amenable to gene editing. <h4>Methods</h4> N...

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Literature Corpus work
ee1c907a-63e3-5759-99d7-9e3a968e57e2
DOI
10.64898/2026.02.16.706000
Open publication

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Establishment of Stable Immortalized Human Choroidal Melanocytes for Ocular ResearchDOI 10.64898/2026.02.16.706000
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